Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling
embryonic and organ development, as well as cancer progression. Genome-wide …

Transcriptional enhanced associate domain (TEAD) transcription factors play important roles
during development, cell proliferation, regeneration, and tissue homeostasis. TEAD …

The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …

RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …

Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial
heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA …

Background Melanoma is the most malignant skin tumor and is difficult to cure with the
alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study …

Background The heterocyclic compounds particularly pyridine displayed clinical and
biological implementation. Pyridine scaffolds have been detected in most relevant drug …

Tumors consist of heterogeneous cell populations, and tumor heterogeneity plays key roles
in regulating tumorigenesis, metastasis, recurrence and resistance to anti-tumor therapies …

Gastric cancer (GC) continues to be the most common gastrointestinal malignancy in China,
and tumor metastases are a major reason for poor prognosis. Circular RNAs (circRNAs) are …