Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …

Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …

The quality and application of super-resolution fluorescence imaging greatly lie in the dyes'
properties, including photostability, brightness, and Stokes shift. Here we report a synergistic …

Sulfoxide-bridged dimeric BODIPYs were developed as a new class of long-wavelength
photoconvertible fluorophores. Upon visible-light irradiation, a sulfoxide moiety was …

Organic fluorophores are indispensable tools in cells, tissue and in vivo imaging, and have
enabled much progress in the wide range of biological and biomedical fields. However …

The specific and covalent labeling of the protein HaloTag with fluorescent probes in living
cells makes it a powerful tool for bioimaging. However, the irreversible attachment of the …

Stimulated emission depletion (STED) nanoscopy has broadened our horizons to unravel
mysterious functions of cellular structures on an unparalleled nanometer scale …

The controlled switching of fluorophores between non-fluorescent and fluorescent states is
central to every super-resolution fluorescence microscopy (nanoscopy) technique, and the …