Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

A major challenge to advance lipid nanoparticles (LNPs) for RNA therapeutics is the
development of formulations that can be produced reliably across the various scales of drug …

Nanotechnology has recently gained increased attention for its capability to effectively
diagnose and treat various tumors. Nanocarriers have been used to circumvent the …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Emerging therapeutics that utilize RNA interference (RNAi) have the potential to treat broad
classes of diseases due to their ability to reversibly silence target genes. In August 2018, the …

The rapid expansion of the available genomic data continues to greatly impact biomedical
science and medicine. Fulfilling the clinical potential of genetic discoveries requires the …

Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

Nanosystems have shown encouraging outcomes and substantial progress in the areas of
drug delivery and biomedical applications. However, the controlled and targeted delivery of …

Gene-silencing with targeted siRNAs has great potential as a therapeutic approach for
various diseases including cancer. However, intracellular delivery of siRNA is challenging …