Tannins as an alternative to antibiotics

AK Farha, QQ Yang, G Kim, HB Li, F Zhu, HY Liu… - Food Bioscience, 2020 - Elsevier
Excessive use of antibiotics has led to the emergence of multidrug-resistant bacteria that are
a serious threat to human health. There is a need to develop efficient antibacterial agents to …

Nonantibiotic prevention and management of recurrent urinary tract infection

N Sihra, A Goodman, R Zakri, A Sahai… - Nature Reviews …, 2018 - nature.com
Urinary tract infections (UTIs) are highly prevalent, lead to considerable patient morbidity,
incur large financial costs to health-care systems and are one of the most common reasons …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal …

J Luo, B Dong, K Wang, S Cai, T Liu, X Cheng, D Lei… - PloS one, 2017 - journals.plos.org
The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling
virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm …

Hordenine: A Novel Quorum Sensing Inhibitor and Antibiofilm Agent against Pseudomonas aeruginosa

JW Zhou, HZ Luo, H Jiang, TK Jian… - Journal of agricultural …, 2018 - ACS Publications
The quorum sensing (QS) inhibitory activity of hordenine from sprouting barley against
foodborne pathogen Pseudomonas aeruginosa was evaluated for the first time here. At …

Plant growth-promoting activity and quorum quenching-mediated biocontrol of bacterial phytopathogens by Pseudomonas segetis strain P6

M Rodríguez, M Torres, L Blanco, V Béjar… - Scientific reports, 2020 - nature.com
Given the major threat of phytopathogenic bacteria to food production and ecosystem
stability worldwide, novel alternatives to conventional chemicals-based agricultural practices …

Various antibacterial mechanisms of biosynthesized copper oxide nanoparticles against soilborne Ralstonia solanacearum

J Chen, S Mao, Z Xu, W Ding - RSC advances, 2019 - pubs.rsc.org
The substantial antimicrobial efficacy of nanoparticles against phytopathogens has been
extensively investigated for advanced agricultural applications. However, few reports have …

Targeting the bacteria–host interface: strategies in anti-adhesion therapy

AM Krachler, K Orth - Virulence, 2013 - Taylor & Francis
Bacterial infections are a major cause of morbidity and mortality worldwide and are
increasingly problematic to treat due to the rise in antibiotic-resistant strains. It becomes …

Plant Derived Natural Products against Pseudomonas aeruginosa and Staphylococcus aureus: Antibiofilm Activity and Molecular Mechanisms

F Guzzo, M Scognamiglio, A Fiorentino, E Buommino… - Molecules, 2020 - mdpi.com
Bacteria are social organisms able to build complex structures, such as biofilms, that are
highly organized surface-associated communities of microorganisms, encased within a self …