From adhesion complex to signaling hub: the dual role of dystroglycan

F Sciandra, M Bozzi, MG Bigotti - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Dystroglycan (DG) is a transmembrane protein widely expressed in multiple cells and
tissues. It is formed by two subunits, α− and β-DG, and represents a molecular bridge …

[HTML][HTML] Deciphering the pathophysiological mechanisms underpinning myoclonus dystonia using pluripotent stem cell-derived cellular models

Z Li, L Abram, KJ Peall - Cells, 2024 - mdpi.com
Dystonia is a movement disorder with an estimated prevalence of 1.2% and is characterised
by involuntary muscle contractions leading to abnormal postures and pain. Only …

Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan

MJM Anderson, AN Hayward, AT Smiley, K Shi… - Structure, 2024 - cell.com
The dystrophin-glycoprotein-complex (DGC), anchored by the transmembrane protein
dystroglycan, functions to mechanically link the extracellular matrix and actin cytoskeleton …

[图书][B] A Role for Cas Adaptor Proteins During the Establishment of the Cortical Glial Scaffold

N Rajabli - 2023 - search.proquest.com
The cerebral cortex, the largest and most elaborate part of the mammalian brain, is
outermost layer of the brain responsible for higher cognitive function such as perception …