Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

Blazing the trail for innovative tuberculosis diagnostics

S Yerlikaya, T Broger, C Isaacs, D Bell, L Holtgrewe… - Infection, 2024 - Springer
The COVID-19 pandemic brought diagnostics into the spotlight in an unprecedented way not
only for case management but also for population health, surveillance, and monitoring. The …

[HTML][HTML] The airborne contagiousness of respiratory viruses: a comparative analysis and implications for mitigation

A Mikszewski, L Stabile, G Buonanno, L Morawska - Geoscience Frontiers, 2022 - Elsevier
The infectious emission rate is a fundamental input parameter for airborne transmission risk
assessment, but data are limited due to reliance on estimates from chance superspreading …

Aerosolization of viable Mycobacterium tuberculosis bacilli by tuberculosis clinic attendees independent of sputum-Xpert Ultra status

B Patterson, R Dinkele, S Gessner… - Proceedings of the …, 2024 - National Acad Sciences
Potential Mycobacterium tuberculosis (Mtb) transmission during different pulmonary
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …

[HTML][HTML] Cough-independent production of viable Mycobacterium tuberculosis in bioaerosol

B Patterson, W Bryden, C Call, A McKerry, B Leonard… - Tuberculosis, 2021 - Elsevier
Background Symptoms of infectious respiratory illnesses are often assumed to drive
transmission. However, production and release of Mycobacterium tuberculosis (Mtb) …

Monodisperse Fluorescent Polystyrene Microspheres for Staphylococcus aureus Aerosol Simulation

S Lu, F Li, B Liu, K Yang, F Tian, Z Cheng, S Ding… - Polymers, 2023 - mdpi.com
Staphylococcus aureus (SA) is one of the most common causes of hospital-acquired
infections and foodborne illnesses and is commonly found in nature in air, dust, and water …

Non-sputum-based samples and biomarkers for detection of Mycobacterium tuberculosis: the hope to improve childhood and HIV-associated tuberculosis diagnosis

GW Kasule, S Hermans, D Semugenze… - European Journal of …, 2024 - Springer
Abstract In 2014, the World Health Organisation (WHO) published target product profiles
(TPP) for development of novel tuberculosis (TB) diagnostics. One of the key highlights is the …

Application of lab-on-chip for detection of microbial nucleic acid in food and environment

L Yang, W Yi, F Sun, M Xu, Z Zeng, X Bi… - Frontiers in …, 2021 - frontiersin.org
Various diseases caused by food-borne or environmental pathogenic microorganisms have
been a persistent threat to public health and global economies. It is necessary to regularly …

Detection of M. tuberculosis in the environment as a tool for identifying high-risk locations for tuberculosis transmission

R Verma, FMF Moreira, AO do Prado Morais… - Science of the Total …, 2022 - Elsevier
Tuberculosis (TB) remains a leading cause of infectious mortality globally, yet most cases
cannot be epidemiologically linked even with extensive contact investigations and whole …

Bioaerosol sampling of patients with suspected pulmonary tuberculosis: a study protocol

B Patterson, A Koch, S Gessner, R Dinkele… - BMC infectious …, 2020 - Springer
Background Tuberculosis (TB) is transmitted in bioaerosols containing Mycobacterium
tuberculosis (Mtb). Despite being central to ongoing TB transmission, no routine diagnostic …