In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

Long-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affects the host …

Orally available antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) are necessary because of the continuous circulation of new variants that challenge …

Abstract Background and Purpose Neutrophil overstimulation plays a crucial role in tissue
damage during severe infections. Because pathogen‐derived neuraminidase (NEU) …

Introduction Pulmonary diseases represent a significant burden to patients and the
healthcare system and are one of the leading causes of mortality worldwide. Particularly, the …

Porcine hemagglutinating encephalomyelitis virus (PHEV) is a highly neurotropic
coronavirus belonging to the genus Betacoronavirus. Similar to pathogenic coronaviruses to …

Coronaviruses (CoVs) have continuously posed a threat to human and animal health.
However, existing antiviral drugs are still insufficient in overcoming the challenges caused …

Poor disease outcomes and lethality are directly related to endothelial dysfunction in
betacoronavirus infections. Here, we investigated the mechanisms underlying the vascular …

Aims Millions of people died during the COVID-19 pandemic, but the vast majority of infected
individuals survived. Now, some consequences of the disease, known as long COVID, are …

Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids
and play an important role on host defense. It has been demonstrated that upon infection or …