WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling

Q Huang, Y Xiao, T Lan, Y Lu, L Huang… - International Journal of …, 2024 - nature.com
Wnt signaling are critical pathway involved in organ development, tumorigenesis, and
cancer progression. WNT7A, a member of the Wnt family, remains poorly understood in …

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia

T Carr, S McGregor, S Dias, M Verykokakis… - Frontiers in …, 2022 - frontiersin.org
T lymphocyte acute lymphoblastic leukemia (T-ALL) is a heterogeneous disease affecting T
cells at multiple stages of their development and is characterized by frequent genomic …

Immunohistochemical Investigation into Protein Expression Patterns of FOXO4, IRF8 and LEF1 in Canine Osteosarcoma

S Brot, J Cobb, AA Alibhai, J Jackson-Oxley, M Haque… - Cancers, 2024 - mdpi.com
Simple Summary There have been limited advances in the diagnosis, prognosis, and
treatment of both canine and human osteosarcoma (OSA), the most common type of primary …

MustSeq, an alternative approach for multiplexible strand-specific 3'end sequencing of mRNA transcriptome confers high efficiency and practicality

L Mai, Y Qiu, Z Lian, C Chen, L Wang, Y Yin, S Wang… - RNA biology, 2021 - Taylor & Francis
ABSTRACT RNA-seq has been widely used to reveal the molecular mechanism of variants
of life process. We have developed an alternative method, MustSeq, which generates …

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in a Murine Model of T Acute Lymphoblastic Leukemia

T Carr, S McGregor, S Dias, M Verykokakis… - bioRxiv, 2021 - biorxiv.org
T lymphocyte acute lymphoblastic leukemia (T-ALL) is a heterogeneous disease affecting T
cells at multiple stages of their development and is characterized by frequent genomic …

Differential Expression of LEF1 Isoforms in Adult Lymphoid and Myeloid Malignancies

S Fırtına, ÖH Ng, Y Erbilgin, İC Haznedaroğlu… - Experimed, 2021 - dergipark.org.tr
Objective: Lymphoid enhancer-binding factor-1 (LEF1) is one of the key regulators of
lymphocyte proliferation and its aberrant ex-pression is a prognostic factor for lymphoid or …

Method for multiplexable strand-specific 3'end sequencing of mrna transcriptome primer set, kit and application thereof

X Pan, MAI Liyao, C Caiming, QIU Yinbing… - US Patent App. 17 …, 2023 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …

Yetişkin Lenfoid ve Miyeloid Malignitelerde LEF1 İzoformlarının Farklı Ekspresyonu

F Sinem, HN Özden, E Yücel, H İbrahim, S Müge - Experimed, 2021 - iupress.istanbul.edu.tr
Amaç: Lenfositlerin çoğalmasındaki önemli düzenleyicilerden biri olan lenfoid güçlendirici
bağlama faktörü-1 (LEF1)'in anormal ekspresyonu, lenfoid veya miyeloid maligniteler için …