The human ATP‐binding cassette (ABC) transporter superfamily

M Dean, K Moitra, R Allikmets - Human mutation, 2022 - Wiley Online Library
The ATP‐binding cassette (ABC) transporter superfamily comprises membrane proteins that
efflux various substrates across extra‐and intracellular membranes. Mutations in ABC genes …

Expression and function of ABC proteins in fish intestine

F Bieczynski, JC Painefilú, A Venturino… - Frontiers in …, 2021 - frontiersin.org
In fish, the intestine is fundamental for digestion, nutrient absorption, and other functions like
osmoregulation, acid-base balance, and excretion of some metabolic products. These …

The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase

JG Park, S Kim, E Jang, SH Choi, H Han, S Ju… - Nature …, 2022 - nature.com
TAPL is a lysosomal ATP-binding cassette transporter that translocates a broad spectrum of
polypeptides from the cytoplasm into the lysosomal lumen. Here we report that, in addition to …

Genome-wide analysis of ATP-binding cassette (ABC) transporters in the sweetpotato whitefly, Bemisia tabaci

L Tian, T Song, R He, Y Zeng, W Xie, Q Wu, S Wang… - BMC genomics, 2017 - Springer
Background ABC transporter superfamily is one of the largest and ubiquitous groups of
proteins. Because of their role in detoxification, insect ABC transporters have gained more …

Functional characterization and osmoregulatory role of the Na+-K+-2Cl cotransporter in the gill of sea lamprey (Petromyzon marinus), a basal vertebrate

CA Shaughnessy… - American Journal of …, 2020 - journals.physiology.org
The present study provides molecular and functional characterization of Na+-K+-2Cl−
cotransporter (NKCC1/Slc12a2) in the gills of sea lamprey (Petromyzon marinus), the most …

Tryptophan metabolism can modulate immunologic tolerance in primitive vertebrate lamprey via IDO-kynurenine-AHR pathway

X Duan, Y Luan, Y Wang, X Wang, P Su, Q Li… - Fish & Shellfish …, 2023 - Elsevier
Tryptophan is mainly degraded through kynurenine pathway (KP) in vertebrates which is
closely related to the nerve and depression, while the studies on immunity is still limited …

A review of osmoregulation in lamprey

D Ferreira-Martins, JM Wilson, SP Kelly… - Journal of Great Lakes …, 2021 - Elsevier
Lamprey are living representatives of the basal vertebrate agnathan lineage. Many lamprey
species are anadromous with a complex life cycle that includes metamorphosis from a …

Identification and functional characterization of ABCC transporters for Cd tolerance and accumulation in Sedum alfredii Hance

T Feng, X He, R Zhuo, G Qiao, X Han, W Qiu, L Chi… - Scientific Reports, 2020 - nature.com
Cd is one of the potential toxic elements (PTEs) exerting great threats on the environment
and living organisms and arising extensive attentions worldwide. Sedum alfredii Hance, a …

Retracted: Circ‐TCF4.85 silencing inhibits cancer progression through microRNA‐486‐5p‐targeted inhibition of ABCF2 in hepatocellular carcinoma

J Gao, C Dai, X Yu, XB Yin, F Zhou - Molecular Oncology, 2020 - Wiley Online Library
The current study aimed to explore the role of the circular RNA circ‐TCF4. 85 and its
downstream target microRNA‐486‐5p (miR‐486‐5p) in hepatocellular carcinoma (HCC) …

Unraveling cellular and molecular mechanisms of acid stress tolerance and resistance in marine species: New frontiers in the study of adaptation to ocean …

S Simonetti, V Zupo, MC Gambi, T Luckenbach… - Marine Pollution …, 2022 - Elsevier
Since the industrial revolution, fossil fuel combustion has led to a 30%-increase of the
atmospheric CO 2 concentration, also increasing the ocean partial CO 2 pressure. The …