[PDF][PDF] Serine-404 Phosphorylation and the R406W Modification in Tau Stabilize the cis-Proline Amide Bond, via Phosphoserine-Proline C–H/O and Proline-Aromatic …
HK Ganguly, MB Elbaum, NJ Zondlo - Interactions. ChemRxiv, 2023 - chemrxiv.org
Tau misfolding, oligomerization, and aggregation are central to the pathology of Alzheimer's
disease (AD), chronic traumatic encephalopathy (CTE), frontotemporal dementia, and other …
disease (AD), chronic traumatic encephalopathy (CTE), frontotemporal dementia, and other …
A strained N-capping motif in α-helices of βαβ-units
AM Kargatov - Journal of Structural Biology, 2024 - Elsevier
A novel helical N-capping motif has been considered. It occurs in the βα-arches of right-
handed βαβ-units and contains an N-cap residue in a sterically strained conformation …
handed βαβ-units and contains an N-cap residue in a sterically strained conformation …
Accommodation of Gly-cis Pro in a designed β-hairpin
Replacement of a single residue in a β-hairpin by Gly-Pro, a 'united-residue'known to be
overrepresented in protein β-sheets as Gly-cisPro without causing much structural distortion …
overrepresented in protein β-sheets as Gly-cisPro without causing much structural distortion …
Proline-Aromatic Sequences Stabilize Turns via C–H/π interactions in both cis-Proline and trans-Proline
HK Ganguly, MB Elbaum, NJ Zondlo - 2023 - chemrxiv.org
In proteins, proline-aromatic sequences exhibit increased frequencies of cis-proline amide
bonds, via proposed C–H/π interactions between the aromatic ring and either the proline …
bonds, via proposed C–H/π interactions between the aromatic ring and either the proline …