Does Lactobacillus Exert a Protective Effect on the Development of Cervical and Endometrial Cancer in Women?
K Frąszczak, B Barczyński, A Kondracka - Cancers, 2022 - mdpi.com
Simple Summary Cervical cancer is the fourth most common cancer in women worldwide.
Tumour-related deaths are most frequent in low-and middle-income countries. Currently …
Tumour-related deaths are most frequent in low-and middle-income countries. Currently …
Probiotic-based vaccines may provide effective protection against COVID-19 acute respiratory disease
S Taghinezhad-S, AH Mohseni… - Vaccines, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2) infection, the
causative agent of COVID-19, now represents the sixth Public Health Emergency of …
causative agent of COVID-19, now represents the sixth Public Health Emergency of …
Twenty years of research on HPV vaccines based on genetically modified lactic acid bacteria: an overview on the gut-vagina axis
S Taghinezhad-S, H Keyvani… - Cellular and Molecular …, 2021 - Springer
Most cervical cancer (CxCa) are related to persistent infection with high-risk human
papillomavirus (HR-HPV) in the cervical mucosa, suggesting that an induction of mucosal …
papillomavirus (HR-HPV) in the cervical mucosa, suggesting that an induction of mucosal …
The First Clinical Use of a Recombinant Lactococcus lactis Expressing Human Papillomavirus Type 16 E7 Oncogene Oral Vaccine: A Phase I Safety and …
A dose-escalation, randomized, double-blind, placebo-controlled phase I clinical trial was
performed in healthy Iranian volunteer women to assess the safety, tolerability, and …
performed in healthy Iranian volunteer women to assess the safety, tolerability, and …
Oral immunization with recombinant Lactococcus lactis NZ9000 expressing human papillomavirus type 16 E7 antigen and evaluation of its immune effects in female …
The ORFs of both native and codon‐optimized E7 genes were successfully fused to
SPusp45 signal peptide and expressed by a nisin‐controlled gene expression system in the …
SPusp45 signal peptide and expressed by a nisin‐controlled gene expression system in the …
Phase 1 safety and immunogenicity trial of recombinant lactococcus lactis expressing human papillomavirus type 16 E6 oncoprotein vaccine
The present study purposed to investigate the safety, tolerability, and immunogenicity of the
therapeutic NZ8123-HPV16-optiE6 vaccine, following oral vaccination. The safety and …
therapeutic NZ8123-HPV16-optiE6 vaccine, following oral vaccination. The safety and …
Protection against human papillomavirus type 16-induced tumors in C57BL/6 mice by mucosal vaccination with Lactococcus lactis NZ9000 expressing E6 oncoprotein
Recombinant strains of Lactococcus lactis NZ9000 that express native and codon-optimized
E6 protein (fused to the SPusp45 secretion signal) were successfully constructed by using …
E6 protein (fused to the SPusp45 secretion signal) were successfully constructed by using …
Strain-specific differences in purification and VLP formation for a quadrivalent recombinant HPV vaccine
K Aghajani, A Asadollahi, T Taghizadeh… - Biochemical …, 2024 - Elsevier
Human papillomavirus (HPV) is responsible for causing various types of cancers, including
cervical cancer. Recombinant HPV vaccines are developed using recombinant DNA …
cervical cancer. Recombinant HPV vaccines are developed using recombinant DNA …
Plasmid Replicons for the Production of Pharmaceutical-Grade pDNA, Proteins and Antigens by Lactococcus lactis Cell Factories
SOD Duarte, GA Monteiro - International Journal of Molecular Sciences, 2021 - mdpi.com
The Lactococcus lactis bacterium found in different natural environments is traditionally
associated with the fermented food industry. But recently, its applications have been …
associated with the fermented food industry. But recently, its applications have been …
Efficient production and optimization of E7 oncoprotein from Iranian human papillomavirus type 16 in Lactococcus lactis using nisin-controlled gene expression (NICE) …
The present work was aimed at investigating the expression and optimization of a human
papillomavirus (HPV) type 16 gene encoding oncoprotein E7 in Lactococcus lactis. We …
papillomavirus (HPV) type 16 gene encoding oncoprotein E7 in Lactococcus lactis. We …