Mechanisms of oxidative processes in meat and toxicity induced by postprandial degradation products: A review

C Papuc, GV Goran, CN Predescu… - … Reviews in food …, 2017 - Wiley Online Library
Antioxidant system loss after slaughtering, reactive species production, cell disruption,
contact with oxygen and light, heme and nonheme iron, and irradiation starts up mainly by 2 …

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

B Halliwell, M Whiteman - British journal of pharmacology, 2004 - Wiley Online Library
Free radicals and other reactive species (RS) are thought to play an important role in many
human diseases. Establishing their precise role requires the ability to measure them and the …

Biomarkers of free radical damage: applications in experimental animals and in humans

LL de Zwart, JHN Meerman, JNM Commandeur… - Free Radical Biology …, 1999 - Elsevier
Free radical damage is an important factor in many pathological and toxicological
processes. Despite extensive research efforts in biomarkers in recent years, yielding …

Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms

U Nair, H Bartsch, J Nair - Mutagenesis, 2004 - academic.oup.com
Abstract In south‐east Asia, Taiwan and Papua New Guinea, smoking, alcohol consumption
and chewing of betel quid with or without tobacco or areca nut with or without tobacco are …

Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives

JH Jeng, MC Chang, LJ Hahn - Oral oncology, 2001 - Elsevier
Betel quid (BQ)-chewing is a popular oral habit with potential links to the occurrence of oral
cancer. Many of the literature-based studies reveal that areca nut (AN) extract may …

Systematic Review of Roles of Arecoline and Arecoline N-Oxide in Oral Cancer and Strategies to Block Carcinogenesis

AMS Ko, HP Tu, YC Ko - Cells, 2023 - mdpi.com
Betel quid and areca nut are complex mixture carcinogens, but little is known about whether
their derived single-agent arecoline or arecoline N-oxide (ANO) is carcinogenic, and the …

Adverse health effects of betel quid and the risk of oral and pharyngeal cancers

PH Chen, Q Mahmood, GL Mariottini… - BioMed research …, 2017 - Wiley Online Library
Global reports estimate 600 million betel quid (BQ) chewers. BQ chewing has been
demonstrated not only to be a risk factor for cancers of the oral cavity and pharynx and oral …

Molecular pathways of oral submucous fibrosis and its progression to malignancy

K Gayathri, N Malathi, V Gayathri, PN Adtani… - Archives of oral …, 2023 - Elsevier
Objective The review aims to comprehend various factors engaged in the alteration of
molecular events resulting in Oral submucous fibrosis (OSMF) and its malignant …

Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer

TT Sreelekha, K Ramadas, M Pandey, G Thomas… - Oral oncology, 2001 - Elsevier
Oral cancer ranks first among all cancers in males and is the third most common among
females in India. Tobacco-derived carcinogens are involved in the development of oral …

Carcinogenic effects of areca nut and its metabolites: a review of the experimental evidence

K Senevirathna, R Pradeep, YA Jayasinghe… - Clinics and …, 2023 - mdpi.com
Oral cancers (OC) are among the most frequent malignancies encountered in Southeast
Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in …