V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022 - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …
HOD Critchley, JA Maybin… - Physiological …, 2020 - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …
L Tengborn, M Blombäck, E Berntorp - Thrombosis research, 2015 - Elsevier
Experience with tranexamic acid, an indirect fibrinolytic inhibitor, started as soon as it was released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …
JA Maybin, HOD Critchley - Human reproduction update, 2015 - academic.oup.com
BACKGROUND Each month the endometrium becomes inflamed, and the luminal portion is shed during menstruation. The subsequent repair is remarkable, allowing implantation to …
LD Bradley, NA Gueye - American journal of Obstetrics and Gynecology, 2016 - Elsevier
In the treatment of women with abnormal uterine bleeding, once a thorough history, physical examination, and indicated imaging studies are performed and all significant structural …
M Livingstone, IS Fraser - Human reproduction update, 2002 - academic.oup.com
Over the past 10 years there has been an upsurge of interest in the mechanisms underlying normal and disturbed menstrual bleeding. These studies have particularly focused on the …
MK Oehler, MCP Rees - Acta obstetricia et gynecologica …, 2003 - Taylor & Francis
Menorrhagia is defined as a'complaint of heavy cyclical menstrual bleeding occurring over several consecutive cycles'. Objectively it is a total menstrual blood loss equal to or greater …
SK Smith - Human Reproduction Update, 1998 - academic.oup.com
Angiogenesis is an essential component of endometrial renewal. The formation of new vessels depends on interactions between various hormones and growth factors, and this …
PG Groothuis, AW Nap, E Winterhager, R Grümmer - Angiogenesis, 2005 - Springer
Endometriosis, defined as the presence of endometrial tissue outside the uterus, is an estrogen-dependent disease which causes pelvic pain and subfertility in women of …