Medicinal significance of benzothiazole scaffold: an insight view

PC Sharma, A Sinhmar, A Sharma… - Journal of enzyme …, 2013 - Taylor & Francis
Heterocycles bearing nitrogen, sulphur and thiazole moieties constitute the core structure of
a number of biologically interesting compounds. Benzothiazole, a group of xenobiotic …

Benzothiazoles as potential antiviral agents

YI Asiri, A Alsayari, AB Muhsinah… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives The recent viral pandemic poses a unique challenge for healthcare providers.
Despite the remarkable progress, the number of novel antiviral agents in the pipeline is …

Synthesis and structure–activity relationships of new antimicrobial active multisubstituted benzazole derivatives

I Yildiz-Oren, I Yalcin, E Aki-Sener… - European Journal of …, 2004 - Elsevier
A series of multisubstituted benzoxazoles, benzimidazoles, and benzothiazoles (5–7) as
non-nucleoside fused isosteric heterocyclic compounds was synthesized and tested for their …

Benzoxazoles and oxazolopyridines in medicinal chemistry studies

CS Demmer, L Bunch - European Journal of Medicinal Chemistry, 2015 - Elsevier
The benzoxazole heterocycle is often found in ligands targeting a plethora of receptors and
enzymes. By analysis of published X-ray structures, this review aims at highlighting key …

Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents

T Ertan, I Yildiz, B Tekiner-Gulbas, K Bolelli… - European journal of …, 2009 - Elsevier
A new series of 5 (or 6)-nitro/amino-2-(substituted phenyl/benzyl) benzoxazole derivatives
(1a–1m, 2a–2l) were synthesized and evaluated for antibacterial and antifungal activities …

Some fused heterocyclic compounds as eukaryotic topoisomerase II inhibitors

A Pinar, P Yurdakul, I Yildiz, O Temiz-Arpaci… - Biochemical and …, 2004 - Elsevier
Our previously synthesized 37 compounds, which are 2, 5, 6-substituted benzoxazole,
benzimidazole, benzothiazole, and oxazolo (4, 5-b) pyridine derivatives, were tested for their …

Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole

JB Bhagyasree, HT Varghese, CY Panicker… - … Acta Part A: Molecular …, 2013 - Elsevier
The optimized molecular structure, vibrational frequencies, corresponding vibrational
assignments of 5-nitro-2-(4-nitrobenzyl) benzoxazole have been investigated experimentally …

Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl) carboxamido] benzoxazoles

S Alper-Hayta, M Arisoy, Ö Temiz-Arpaci, I Yildiz… - European journal of …, 2008 - Elsevier
The synthesis and antimicrobial activity of a new series of 2-(substitutedphenyl/benzyl)-5-[(2-
benzofuryl) carboxamido] benzoxazole derivatives 3–12 were described. The in vitro …

Exploring the efficacy of benzimidazolone derivative as corrosion inhibitors for copper in a 3.5 Wt.% NaCl solution: a comprehensive experimental and theoretical …

M Adardour, M Lasri, M Ait Lahcen, M Maatallah… - Molecules, 2023 - mdpi.com
This study focuses on the synthesis, theoretical analysis, and application of the corrosion
inhibitor known as benzimidazolone, specifically 1-(cyclohex-1-enyl)-1, 3-dihydro-2 H …

[PDF][PDF] The chemistry and biological significance of imidazole, benzimidazole, benzoxazole, tetrazole and quinazolinone nucleus

R Ranjith - J. Chem. Pharm. Res, 2016 - researchgate.net
The imidazole, benzimidazole, benzoxazole, tetrazole and quinazolinone are heterocyclic
aromatic organic compounds. It is an important pharmacophore and privileged structure in …