Tumor immunotherapy, especially immune checkpoint inhibitors (ICIs), has been applied in
clinical practice, but low response to immune therapies remains a thorny issue. Oncolytic …

Immunologically inert or cold tumors pose a substantial challenge to the effectiveness of
immunotherapy. The use of oncolytic viruses (OVs) to induce immunogenic cell death (ICD) …

A malignant tumor is a complex systemic disease involving the nervous system, which
regulates nerve signals. Cancer neuroscience is a field that explores the interactions …

Purpose Phototherapy has remarkable advantages in cancer treatment, owing to its high
efficiency and minimal invasiveness. Indocyanine green (ICG) plays an important role in …

Oncolytic viruses (OVs) have emerged as a powerful tool in cancer therapy. Characterized
with the unique abilities to selectively target and lyse tumor cells, OVs can expedite the …

For decades, researchers have studied how brain tumors, the immune system, and drugs
interact. With the advances in cancer neuroscience, which centers on defining and …

Oncolytic viral therapy (OVT) is an emerging precision therapy for aggressive and recurrent
cancers. However, its clinical efficacy is hindered by the complexity of tumor-virus-immune …

Nonostante i progressi ottenuti, alcuni tumori rimangono ad oggi difficili da trattare e
associati ad una prognosi infausta. Tra questi rientra il glioblastoma per il quale, al …