Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

DM Norden, MM Muccigrosso, JP Godbout - Neuropharmacology, 2015 - Elsevier
Glia of the central nervous system (CNS) help to maintain homeostasis in the brain and
support efficient neuronal function. Microglia are innate immune cells of the brain that …

Prevalence of and risk factors for anxiety and depressive disorders after traumatic brain injury: a systematic review

AC Scholten, JA Haagsma, MC Cnossen… - Journal of …, 2016 - liebertpub.com
This review examined pre-and post-injury prevalence of, and risk factors for, anxiety
disorders and depressive disorders after traumatic brain injury (TBI), based on evidence …

Rates of major depressive disorder and clinical outcomes following traumatic brain injury

CH Bombardier, JR Fann, NR Temkin, PC Esselman… - Jama, 2010 - jamanetwork.com
Context Uncertainties exist about the rates, predictors, and outcomes of major depressive
disorder (MDD) among individuals with traumatic brain injury (TBI). Objective To describe …

[PDF][PDF] Recurrent concussion and risk of depression in retired professional football players

KM Guskiewicz, SW Marshall, J Bailes… - Medicine and science …, 2007 - regenexx.com
Recurrent Concussion and Risk of Depression in Retired Professional Football Players
Page 1 Clinically Relevant Recurrent Concussion and Risk of Depression in Retired …

Major depression following traumatic brain injury

RE Jorge, RG Robinson, D Moser… - Archives of general …, 2004 - jamanetwork.com
Backgroud Major depression is a frequent psychiatric complication among patients with
traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major …

Axis I and II psychiatric disorders after traumatic brain injury: a 30-year follow-up study

S Koponen, T Taiminen, R Portin… - American journal of …, 2002 - Am Psychiatric Assoc
OBJECTIVE: Patients who had suffered traumatic brain injury were evaluated to determine
the occurrence of psychiatric disorders during a 30-year follow-up. METHOD: Sixty patients …

Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia

AM Fenn, JC Gensel, Y Huang, PG Popovich… - Biological …, 2014 - Elsevier
Background Traumatic brain injury (TBI) is associated with a higher incidence of depression.
The majority of individuals who suffer a TBI are juveniles and young adults, and thus, the risk …

Rate of psychiatric illness 1 year after traumatic brain injury

S Deb, I Lyons, C Koutzoukis, I Ali… - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Neurobehavioral symptoms are not uncommon after a traumatic brain injury.
However, psychiatric syndromes per se have rarely been studied in patients with such an …

Psychiatric disorders following traumatic brain injury: their nature and frequency

R Whelan-Goodinson, J Ponsford… - The Journal of head …, 2009 - journals.lww.com
Psychiatric Disorders Following Traumatic Brain Injury: Thei... : The Journal of Head Trauma
Rehabilitation Psychiatric Disorders Following Traumatic Brain Injury: Their Nature and …

Treatment for depression after traumatic brain injury: a systematic review

JR Fann, T Hart, KG Schomer - Journal of neurotrauma, 2009 - liebertpub.com
The aim of this systematic review was to critically evaluate the evidence on interventions for
depression following traumatic brain injury (TBI) and provide recommendations for clinical …