Background: Venous thromboembolism (VTE) complicates∼ 1.2 of every 1000 deliveries.
Despite these low absolute risks, pregnancy-associated VTE is a leading cause of maternal …

1Oxford Haemophilia and Thrombosis Centre, Churchill Hospital, Oxford, UK, 2Haemostasis
Research Unit, Haematology Department, University College London, London, UK, 3Centre …

Background The use of anticoagulant therapy during pregnancy is challenging because of
the potential for both fetal and maternal complications. This guideline focuses on the …

Thrombophilia is considered as a condition predisposing to the development of thrombosis.
Arterial thrombosis usually occurs after the erosion or rupture of an atherosclerotic plaque …

Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep
vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention …

Objective To provide evidence to support updated guidelines for the management of
pregnant women with hereditary thrombophilia in order to reduce the risk of a first venous …

Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to
activated Protein C and an increased risk for venous thromboembolism. Deep venous …

Background In about a third of patients with venous thromboembolism, the cause of the
disorder is unexplained. In patients with atherosclerosis, activation of both platelets and …

The annual incidence of venous thrombosis, one of the leading causes of mortality and
morbidity, increases from 1 per 100,000 during childhood to 1 per 100 in old age. 1 In this …

Deep vein thrombosis and its sequelae pulmonary embolism and post-thrombotic syndrome
are some of the most common disorders. A thrombus either arises spontaneously or is …