DNA methylation methods: Global DNA methylation and methylomic analyses
S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …
significant involvement for numerous biological processes in health and disease. The …
One-carbon metabolism and epigenetics
The function of one-carbon metabolism is that of regulating the provision of methyl groups
for biological methylation reactions including that of DNA and histone proteins. Methylation …
for biological methylation reactions including that of DNA and histone proteins. Methylation …
Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction
The epigenetic DNA modification 5-hydroxymethylcytosine (5hmC) has crucial roles in
development and gene regulation,,,,,,. Quantifying the abundance of this epigenetic mark at …
development and gene regulation,,,,,,. Quantifying the abundance of this epigenetic mark at …
The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium
AM Retis-Resendiz, IN González-García… - Clinical …, 2021 - Springer
Background The human endometrium is a highly dynamic tissue whose function is mainly
regulated by the ovarian steroid hormones estradiol and progesterone. The serum levels of …
regulated by the ovarian steroid hormones estradiol and progesterone. The serum levels of …
DNA methylation in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease facilitated by
aberrant immune responses directed against cells and tissues, resulting in inflammation and …
aberrant immune responses directed against cells and tissues, resulting in inflammation and …
Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling
MJ Longley, J Lee, J Jung, FW Lohoff - Addiction biology, 2021 - Wiley Online Library
Alcohol use disorder (AUD) is a major contributor to morbidity and mortality worldwide.
Although there is a heritable component, the etiology of AUD is complex and can involve …
Although there is a heritable component, the etiology of AUD is complex and can involve …
Autophagy-associated biomarkers ULK2, UVRAG, and miRNAs miR-21, miR-126, and miR-374: Prognostic significance in glioma patients
As the pioneering study from Pakistan, our research distinctly focuses on validating the roles
of autophagy-associated genes and MicroRNAs (miRs) in the unique context of our …
of autophagy-associated genes and MicroRNAs (miRs) in the unique context of our …
Label-free and template-free chemiluminescent biosensor for sensitive detection of 5-hydroxymethylcytosine in genomic DNA
C Li, Y Dong, X Zou, X Luo, D Shen, J Hu… - Analytical …, 2021 - ACS Publications
5-Hydroxymethylcytosine (5hmC) is a modified base present at low levels in various
mammalian cells, and it plays essential roles in gene expression, DNA demethylation, and …
mammalian cells, and it plays essential roles in gene expression, DNA demethylation, and …
5-methylcytosine and 5-hydroxymethylcytosine in brains of patients with multiple system atrophy and patients with Parkinson's disease
Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder of unknown
etiology, characterized pathologically by α-synuclein aggregates preferentially found in …
etiology, characterized pathologically by α-synuclein aggregates preferentially found in …
DNA methylation and inflammatory skin diseases
JS Mervis, JS McGee - Archives of dermatological research, 2020 - Springer
Epigenetics is the study of heritable changes in gene expression that do not originate from
alternations in the DNA sequence. Epigenetic modifications include DNA methylation …
alternations in the DNA sequence. Epigenetic modifications include DNA methylation …