Placentation is a key and tightly regulated process that ensures the normal development of
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in
many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been …

Excess reactive oxygen species production and free radical formation can lead to oxidative
stress that can damage cells, tissues, and organs. Cellular oxidative stress is defined as the …

SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

The porosity of liver sinusoidal endothelial cells (LSEC) ensures bidirectional passive
transport of lipoproteins, drugs and solutes between the liver capillaries and the liver …

Prostate cancer is the second most common malignancy in men worldwide. Prostate cancer
can be treated by surgery, radiotherapy and hormone therapy. The latter, in the form of …

Functional regulation and structural maintenance of the different organelles in plants
contribute directly to plant development, reproduction and stress responses. To ensure …

NAD+-dependent deacetylase sirtuin-1 (Sirt1) belongs to the sirtuins family, known to be
longevity regulators, and exerts a key role in the prevention of vascular aging. By aging, the …

Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS)
through its metabolites. This process leads to steatosis and liver inflammation, which are …