Mitragynine, is a naturally occurring indole alkaloid that can be isolated from the leaves of a
psychoactive medicinal plant. Mitragyna speciosa, also known as kratom, is found to …

Abstract Purpose of Review Kratom, a preparation of the leaves collected from the Southeast
Asian plant Mitragyna speciosa, has increased in use within the United States (US) …

Importance Kratom products, which are sold legally in most of the US, contain alkaloids with
opioidergic, adrenergic, and serotonergic activity. Millions of people use kratom to relieve …

Abstract Kratom (Mitragyna speciosa Korth.) use has increased substantially over the past
decade outside of its indigenous regions, especially for the self-treatment of psychiatric …

Monoterpene indole alkaloids (MIAs) make up a highly bioactive class of metabolites
produced by a range of tropical and subtropical plants. The corynanthe-type MIAs are a …

Background “Kratom” commonly refers to the botanical Mitragyna speciosa, native to
Southeast Asia, which is increasingly used globally for its unique pharmacological effects …

Alcohol use disorder (AUD) accounts for nearly 4.7% of all deaths and imposes a huge
economic burden on society. Despite the magnitude of the problem, only a few Food and …

Abstract Kratom (Mitragyna speciosa, Korth.) is a tropical tree that is indigenous to Southeast
Asia. When ingested, kratom leaves or decoctions from the leaves have been reported to …

The major groups of NPS discussed include synthetic cannabinoids, synthetic cathinones,
synthetic opioids, piperazines, phenethylamines, phencyclidine-type substances, plant …

Methamphetamine (METH) consumption is associated with aggression. Decoction derived
from the kratom (Mitragyna speciosa Korth.) leaf has been used as a METH substitute in …