Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …

Ionizing radiation is known to cause DNA damage, yet the mechanisms underlying potential
transgenerational effects of exposure have been scarcely studied. Previously, we observed …

Peripheral nerves regenerate successfully; however, clinical outcome after injury is poor. We
demonstrated that low-dose ionizing radiation (LDIR) promoted axon regeneration and …

DNA methylation is a key epigenetic mechanism, needed for proper control over the
expression of genetic information and silencing of repetitive elements. Exposure to ionizing …

Human deep space and planetary travel is limited by uncertainties regarding the health risks
associated with exposure to galactic cosmic radiation (GCR), and in particular the high …

We herein attempted to identify the lowest radiation dose causing molecular changes in the
living body. We investigated the effects of radiation in human cells, animals, and humans …

Transposable elements (TEs) are repetitive DNA sequences capable of changing position in
host genomes, thereby causing mutations. TE insertions typically have deleterious effects …

Purpose: In the late 1990s, it had become clear that the long-standing paradigm for the
action of radiation on living cells and organisms did not have sufficient power to explain the …

Long Interspersed Nuclear Element 1 (LINE-1) retrotransposons are the major repetitive
elements in mammalian genomes. LINE-1s are well-accepted as driving forces of evolution …