Sex differences in cancer mechanisms
JB Rubin, JS Lagas, L Broestl, J Sponagel… - Biology of sex …, 2020 - Springer
We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …
single histological subtype. With the current emphasis on developing personalized …
Extensive recoding of the neural proteome in cephalopods by RNA editing
JJC Rosenthal, E Eisenberg - Annual Review of Animal …, 2023 - annualreviews.org
The coleoid cephalopods have the largest brains, and display the most complex behaviors,
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …
Landscape of adenosine-to-inosine RNA recoding across human tissues
O Gabay, Y Shoshan, E Kopel, U Ben-Zvi… - Nature …, 2022 - nature.com
RNA editing by adenosine deaminases changes the information encoded in the mRNA from
its genomic blueprint. Editing of protein-coding sequences can introduce novel, functionally …
its genomic blueprint. Editing of protein-coding sequences can introduce novel, functionally …
Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity
Abstract Adenosine-to-inosine (A-to-I) RNA editing by the adenosine deaminase that acts on
RNA (ADAR) enzymes is a common RNA modification, preventing false activation of the …
RNA (ADAR) enzymes is a common RNA modification, preventing false activation of the …
ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism
V Tassinari, V Cesarini, S Tomaselli, Z Ianniello… - Genome biology, 2021 - Springer
Abstract Background N 6-methyladenosine (m6A) and adenosine-to-inosine (A-to-I) RNA
editing are two of the most abundant RNA modification events affecting adenosines in …
editing are two of the most abundant RNA modification events affecting adenosines in …
REDIportal: millions of novel A-to-I RNA editing events from thousands of RNAseq experiments
RNA editing is a relevant epitranscriptome phenomenon able to increase the transcriptome
and proteome diversity of eukaryotic organisms. ADAR mediated RNA editing is widespread …
and proteome diversity of eukaryotic organisms. ADAR mediated RNA editing is widespread …
Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal
RNA editing is a widespread post-transcriptional mechanism able to modify transcripts
through insertions/deletions or base substitutions. It is prominent in mammals, in which …
through insertions/deletions or base substitutions. It is prominent in mammals, in which …
RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS
Members of the ADAR family of double-stranded RNA–binding proteins regulate one of the
most abundant RNA modifications in humans, the deamination of adenosine to inosine …
most abundant RNA modifications in humans, the deamination of adenosine to inosine …
[HTML][HTML] ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance
JCI - ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell
maintenance Go to JCI Insight About Editors Consulting Editors For authors Publication ethics …
maintenance Go to JCI Insight About Editors Consulting Editors For authors Publication ethics …
ADAR-mediated RNA editing of DNA: RNA hybrids is required for DNA double strand break repair
S Jimeno, R Prados-Carvajal… - Nature …, 2021 - nature.com
The maintenance of genomic stability requires the coordination of multiple cellular tasks
upon the appearance of DNA lesions. RNA editing, the post-transcriptional sequence …
upon the appearance of DNA lesions. RNA editing, the post-transcriptional sequence …