Although influenza is primarily considered a respiratory infection and causes significant
respiratory mortality, evidence suggests that influenza has an additional burden due to …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Background Estimates of influenza-associated mortality are important for national and
international decision making on public health priorities. Previous estimates of 250 000–500 …

Background Acute myocardial infarction can be triggered by acute respiratory infections.
Previous studies have suggested an association between influenza and acute myocardial …

Importance Cardiovascular deaths and influenza epidemics peak during winter in temperate
regions. Objectives To quantify the temporal association between population increases in …

The effects of aging on the immune system are manifest at multiple levels that include
reduced production of B and T cells in bone marrow and thymus and diminished function of …

Using a model developed for estimating solar inactivation of viruses of biodefense concerns,
we calculated the expected inactivation of SARS‐CoV‐2 virus, cause of COVID‐19 …

People aged 60 and older represent over 11% of the world population and it is expected to
rise 22% by 2050. Population aging is associated to an increased frequency of age-related …

Excess mortality studies provide crucial information regarding the health burden of
pandemics and other large-scale events. Here, we use time series approaches to separate …

Given the" inborn" nature of the innate immune system, it is surprising to find that innate
immune function does in fact change with age. Similar patterns of distinct Toll-like-receptor …