Schizophrenia is a heritable neurocognitive disorder affecting about 1% of the population,
and usually has an onset age at around 21–25 in males and 25–30 in females. Recent …

Background Bipolar disorder (BD) is characterized by intensive mood fluctuations. While
hormones imbalance plays important role in the mood swings, it is unknown whether …

Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early
adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease …

Objective We aim to compare the psychiatric antecedents of schizophrenia (SZ) and bipolar
disorder (BD). Methods Using the Rochester Epidemiology Project, we searched for …

Alcohol consumption has a key role in more than 200 diseases and health injuries, being an
important factor for social and public health costs. Studies with clinical populations show an …

Problems in mental health and socioeconomic health inequalities during childhood and
adolescence are receiving important scientific and political attention. This in mind, we study …

Objective Accurate information on the frequency and prevalence of manic or mixed episodes
is important for therapeutic, prognostic, and safety concerns. We aimed to estimate the risk of …

Aim We investigated the predictive value of polygenic risk scores (PRS) derived from the
schizophrenia GWAS (Trubetskoy et al., 2022)(SCZ3) for phenotypic traits of bipolar disorder …

Recent studies showed that genetic polymorphism of 5, 10-methylenetetrahydrofolate
reductase (MTHFR) is related to attention-deficit hyperactivity disorder (ADHD), bipolar …

(1) Background: Bipolar disorder (BD) is divided into type I (BD-I) and type II (BD-II). Polarity
at onset (PO) is a proposal to specify the clinical course of BD, based on the type of the first …