The aim of the present study was to investigate how different polymers affect the dissociation
of cocrystals prepared by co-spray-drying active pharmaceutical ingredient (API), coformer …

Highlights•Solvent solution crystallization allows best control of material attributes of co-
crystals.•Crystal structures of co-crystals directly govern mechanical properties.•Tabletability …

The influence of temperature and solvent on the solid–liquid phase diagram of the 1: 1
sulfamethazine–salicylic acid co-crystal has been investigated. Ternary phase diagrams of …

Caffeine co‐crystal formation with other compounds is investigated in this study using a
variety of machine learning (ML) methods. A total of 140 caffeine co‐crystal data points are …

Objective The focus of this study was to investigate the possibility of producing ibuprofen-
nicotinamide (IBU-NIC) and ibuprofen-isonicotinamide (IBU-INA) cocrystal-containing …

Formulation of a cocrystal into a solid pharmaceutical dosage form entails numerous
processing steps during which there is risk of dissociation. In an effort to reduce the number …

Several studies have demonstrated the feasibility of in situ co-crystallization in different
pharmaceutical processes such as spray drying, hot melt extrusion, and fluidized bed …

Leprosy, caused by Mycobacterium leprae, despite being a curable disease when treated
can induce peripheral neuropathy. However, the medicines used in polychemotherapy …

Multi-drug therapy involves the simultaneous or sequential administration of two or more
drugs with similar or different mechanisms of action and is efficient in combating various …