Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

KE Holt, H Wertheim, RN Zadoks… - Proceedings of the …, 2015 - National Acad Sciences
Klebsiella pneumoniae is now recognized as an urgent threat to human health because of
the emergence of multidrug-resistant strains associated with hospital outbreaks and …

Hypervirulence and hypermucoviscosity: Two different but complementary Klebsiella spp. phenotypes?

JC Catalán-Nájera, U Garza-Ramos… - Virulence, 2017 - Taylor & Francis
Since the hypermucoviscous variants of Klebsiella pneumoniae were first reported, many
cases of primary liver abscesses and other invasive infections caused by this pathogen have …

Klebsiella pneumoniae population genomics and antimicrobial-resistant clones

KL Wyres, KE Holt - Trends in microbiology, 2016 - cell.com
Antimicrobial-resistant Klebsiella pneumoniae (Kp) has emerged as a major global public
health problem. While resistance can occur across a broad range of Kp clones, a small …

Klebsiella variicola: an emerging pathogen in humans

N Rodríguez-Medina, H Barrios-Camacho… - Emerging microbes & …, 2019 - Taylor & Francis
The Klebsiella pneumoniae complex comprises seven K. pneumoniae-related species,
including K. variicola. K. variicola is a versatile bacterium capable of colonizing different …

Whole-genome sequencing of human clinical Klebsiella pneumoniae isolates reveals misidentification and misunderstandings of Klebsiella pneumoniae, Klebsiella …

SW Long, SE Linson, M Ojeda Saavedra, C Cantu… - Msphere, 2017 - Am Soc Microbiol
Klebsiella pneumoniae is a major threat to public health, causing significant morbidity and
mortality worldwide. The emergence of highly drug-resistant strains is particularly …

mcr-1.2, a New mcr Variant Carried on a Transferable Plasmid from a Colistin-Resistant KPC Carbapenemase-Producing Klebsiella pneumoniae Strain of Sequence …

V Di Pilato, F Arena, C Tascini… - Antimicrobial agents …, 2016 - Am Soc Microbiol
ABSTRACT A novel mcr variant, named mcr-1.2, encoding a Gln3-to-Leu functional variant
of MCR-1, was detected in a KPC-3-producing ST512 Klebsiella pneumoniae isolate …

Identification of Klebsiella pneumoniae, Klebsiella quasipneumoniae, Klebsiella variicola and Related Phylogroups by MALDI-TOF Mass Spectrometry

C Rodrigues, V Passet, A Rakotondrasoa… - Frontiers in …, 2018 - frontiersin.org
Klebsiella pneumoniae (phylogroup Kp1), one of the most problematic pathogens
associated with antibiotic resistance worldwide, is phylogenetically closely related to K …

Klebsiella variicola Is a Frequent Cause of Bloodstream Infection in the Stockholm Area, and Associated with Higher Mortality Compared to K. pneumoniae

M Maatallah, M Vading, MH Kabir, A Bakhrouf, M Kalin… - PloS one, 2014 - journals.plos.org
Clinical isolates of Klebsiella pneumoniae are divided into three phylogroups and differ in
their virulence factor contents. The aim of this study was to determine an association …