Highlights of the latest developments in radiopharmaceuticals for infection imaging and future perspectives

E Dadachova, DEN Rangel - Frontiers in Medicine, 2022 - frontiersin.org
COVID-19 pandemic has heightened the interest toward diagnosis and treatment of
infectious diseases. Nuclear medicine with its powerful scintigraphic, single photon emission …

99mTc‐labeled antibiotics for infection diagnosis: Mechanism, action, and progress

SAR Naqvi - Chemical Biology & Drug Design, 2022 - Wiley Online Library
Discovery of penicillin marked a turning point in the history of infection therapy which also
led to the emergence of bacterial resistance. It is now 100 years to fight with ever‐muted …

Visualizing and quantifying antimicrobial drug distribution in tissue

BA Kuzma, IJ Pence, DA Greenfield, A Ho… - Advanced Drug Delivery …, 2021 - Elsevier
The biodistribution and pharmacokinetics of drugs are vital to the mechanistic understanding
of their efficacy. Measuring antimicrobial drug efficacy has been challenging as plasma drug …

Recent Advancements in Radiopharmaceuticals for Infection Imaging

E Dadachova, DEN Rangel - Intracellular Pathogens: Methods and …, 2024 - Springer
COVID-19 pandemic has heightened the interest toward diagnosis and treatment of
infectious diseases. Nuclear medicine, with its powerful scintigraphic, single photon …

Susceptibility of 99mTc-Ciprofloxacin for Common Infection Causing Bacterial Strains Isolated from Clinical Samples: an In Vitro and In Vivo Study

SAR Naqvi, S Roohi, H Sabir, SA Shahzad… - Applied biochemistry …, 2019 - Springer
Abstract 99m Tc-ciprofloxacin scintigraphy is useful in the detection of gram-positive and
gram-negative bacterial infections and also for differentiating the infection from aseptic …

Radiosynthesis and Biodistribution of 99mTc-Metronidazole as an Escherichia coli Infection Imaging Radiopharmaceutical

A Iqbal, SAR Naqvi, R Rasheed, A Mansha… - Applied biochemistry …, 2018 - Springer
Bacterial infection poses life-threatening challenge to humanity and stimulates to the
researchers for developing better diagnostic and therapeutic agents complying with existing …

Technetium‐99m radiolabeling and biological study of epirubicin for in vivo imaging of multi‐drug‐resistant Staphylococcus aureus infections via single photon …

NUH Khan, SAR Naqvi, S Roohi… - Chemical Biology & …, 2019 - Wiley Online Library
The development of functional imaging is a promising strategy for diagnosis and treatment of
infectious and cancerous diseases. In this study, epirubicin was developed as a [99mTc] …

Exploring the in-vitro anti-diabetic and anti-bacterial potential of a bromothiophene pyrazolo-pyridine derivative and its complex for radiopharmaceutical applications

I Rafique, T Maqbool, SK Rizvi, S Tariq… - … of Radioanalytical and …, 2024 - Springer
Abstract This study reports 4-(5-bromothiophen-2-yl)-3-methyl-1-1 H-pyrazolo [3, 4-b]
pyridine-6-carbohydrazide (SBrHZD) as an imaging probe with diverse biological potential …

[PDF][PDF] Radiolabeling of benzylpenicillin with lutetium-177: Quality control and biodistribution study to develop theranostic infection imaging agent

MA Shahzad, SAR Naqvi, R Rasheed, M Yameen… - Pak J Pharm …, 2017 - academia.edu
Benzylpenicillin acts through binding with beta-lactamase enzyme and inhibiting the
bacterial cell wall biosynthesis. Therefore, the radiolabeling of benzylpenicillin with lutetium …

Technetium-99m radiopharmaceuticals: a review on basic and applied aspects

M Khan, Q Mehmood - The Nucleus, 2019 - thenucleuspak.org.pk
BIOLOGY OF LEMON MIGRANT BUTTERFLY (CATOPSILIA CROCALE CRAMER) IN THE
LABORATORY Page 1 The Nucleus 56, No. 4 (2019) 163-171 www.thenucleuspak.org.pk 163 …