There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

The sublingual and buccal routes of administration have significant advantages for both
local and systemic drug delivery. They have shown to be an effective alternative to the …

Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer; it involves
damage to oral epithelial cells due to accumulation of multiple genetic mutations in the cells …

Oral squamous cell carcinoma (OSCC), which encompasses the oral cavity-derived
malignancies, is a devastating disease causing substantial morbidity and mortality in both …

Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of
morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5 …

Simple Summary Oral cancer is a major cause of death worldwide. The major challenges
associated with the conventionally used treatment modalities include the recurrence of the …

Buccal drug-delivery systems present a promising approach for the drug delivery to the
buccal mucosa, addressing oral cavity-specific problems, enabling systemic delivery and …

Mucin networks are viscoelastic fibrillar aggregates formed through the complex self-
association of biopolymeric glycoprotein chains. The networks form a lubricious, hydrated …

The improvement of mucoadhesive buccal formulations has attracted profound interest in
recent years. Drug permeability and controlled drug release via this route of administration …

The present study focused on the development of a mucoadhesive patch of methotrexate
(MTX) for targeted delivery in oral cancer. Initially, MTX‑loaded liposomes were prepared …