Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

The neuroscience community has witnessed a tremendous expansion of glia research. Glial
cells are now on center stage with leading roles in the development, maturation, and …

Decreasing the activation of pathology-activated microglia is crucial to prevent chronic
inflammation and tissue scarring. In this study, we used a stab wound injury model in …

In contrast to mammals, the adult zebrafish brain shows neurogenic activity in a multitude of
niches present in almost all brain subdivisions. Irrespectively, constitutive neurogenesis in …

Animal models contribute greatly to our understanding of brain development and function as
well as its dysfunction in neurological diseases. Epilepsy research is a very good example of …

Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and
fishes), but not in mammals. Activation of the innate immune system promotes regenerative …

In mammals, perivascular cell-derived scarring after spinal cord injury impedes axonal
regrowth. In contrast, the extracellular matrix (ECM) in the spinal lesion site of zebrafish is …

The zebrafish telencephalon is composed of highly specialized subregions that regulate
complex behaviors such as learning, memory, and social interactions. The transcriptional …

Radial glia is a cell type traditionally associated with the developing nervous system,
particularly with the formation of cortical layers in the mammalian brain. Nonetheless, some …

Neurogenesis comprises many highly regulated processes including proliferation,
differentiation, and maturation. However, the transcriptional landscapes underlying brain …