Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?

T Róg, I Vattulainen - Chemistry and physics of lipids, 2014 - Elsevier
Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

[HTML][HTML] Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels

F Zakany, T Kovacs, G Panyi, Z Varga - … BBA)-Molecular and Cell Biology of …, 2020 - Elsevier
As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …

Cyclodextrins: Only pharmaceutical excipients or full-fledged drug candidates?

T Kovacs, P Nagy, G Panyi, L Szente, Z Varga… - Pharmaceutics, 2022 - mdpi.com
Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive
pharmaceutical applications due to their unique truncated cone-shaped structure with a …

Roles of sterol derivatives in regulating the properties of phospholipid bilayer systems

TT Bui, K Suga, H Umakoshi - Langmuir, 2016 - ACS Publications
Liposomes are considered an ideal biomimetic environment and are potential functional
carriers for important molecules such as steroids and sterols. With respect to the regulation …

Atomic-level simulation of current–voltage relationships in single-file ion channels

MØ Jensen, V Jogini, MP Eastwood… - Journal of General …, 2013 - rupress.org
The difficulty in characterizing ion conduction through membrane channels at the level of
individual permeation events has made it challenging to elucidate the mechanistic principles …

[HTML][HTML] Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast

M Szomek, P Reinholdt, HL Walther, HA Scheidt… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Natamycin is a polyene macrolide, widely employed to treat fungal keratitis and other yeast
infections as well as to protect food products against fungal molds. In contrast to other …

Sensing cholesterol-induced rigidity in model membranes with time-resolved fluorescence spectroscopy and microscopy

B Biswas, D Shah, SJ Cox-Vázquez… - Journal of Materials …, 2024 - pubs.rsc.org
Here, we report the characterization of cholesterol levels on membrane fluidity with a twisted
intramolecular charge transfer (TICT) membrane dye, namely DI-8-ANEPPS, using …

Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides

F Zakany, IM Mándity, Z Varga, G Panyi, P Nagy… - Cells, 2023 - mdpi.com
Every cell biological textbook teaches us that the main role of the plasma membrane is to
separate cells from their neighborhood to allow for a controlled composition of the …

A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs

M Jafurulla, G Aditya Kumar, BD Rao… - … Modulation of Protein …, 2019 - Springer
G protein-coupled receptors (GPCRs) are the largest and a diverse family of proteins
involved in signal transduction across biological membranes. GPCRs mediate a wide range …

[图书][B] Liposomes, lipid bilayers and model membranes: from basic research to application

G Pabst, N Kučerka, MP Nieh, J Katsaras - 2014 - books.google.com
As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …