Meiosis: dances between homologs

D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Meiotic recombination: mixing it up in plants

Y Wang, GP Copenhaver - Annual Review of Plant Biology, 2018 - annualreviews.org
Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

K Choi, X Zhao, AJ Tock, C Lambing… - Genome …, 2018 - genome.cshlp.org
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …

Next generation breeding

D Barabaschi, A Tondelli, F Desiderio, A Volante… - Plant Science, 2016 - Elsevier
The genomic revolution of the past decade has greatly improved our understanding of the
genetic make-up of living organisms. The sequencing of crop genomes has completely …

Meta‐analysis of chromosome‐scale crossover rate variation in eukaryotes and its significance to evolutionary genomics

Q Haenel, TG Laurentino, M Roesti… - Molecular ecology, 2018 - Wiley Online Library
Understanding the distribution of crossovers along chromosomes is crucial to evolutionary
genomics because the crossover rate determines how strongly a genome region is …

[HTML][HTML] Counting on crossovers: controlled recombination for plant breeding

E Taagen, AJ Bogdanove, ME Sorrells - Trends in plant science, 2020 - cell.com
Crossovers (COs), that drive genetic exchange between homologous chromosomes, are
strongly biased toward subtelomeric regions in plant species. Manipulating the rate and …

Massive crossover elevation via combination of HEI10 and recq4a recq4b during Arabidopsis meiosis

H Serra, C Lambing, CH Griffin… - Proceedings of the …, 2018 - National Acad Sciences
During meiosis, homologous chromosomes undergo reciprocal crossovers, which generate
genetic diversity and underpin classical crop improvement. Meiotic recombination initiates …

Genetic Adaptation Associated with Genome-Doubling in Autotetraploid Arabidopsis arenosa

JD Hollister, BJ Arnold, E Svedin, KS Xue… - PLoS …, 2012 - journals.plos.org
Genome duplication, which results in polyploidy, is disruptive to fundamental biological
processes. Genome duplications occur spontaneously in a range of taxa and problems such …

A few of our favorite things: Pairing, the bouquet, crossover interference and evolution of meiosis

D Zickler, N Kleckner - Seminars in cell & developmental biology, 2016 - Elsevier
Meiosis presents many important mysteries that await elucidation. Here we discuss two such
aspects. First, we consider how the current meiotic program might have evolved. We …

The challenge of evolving stable polyploidy: could an increase in “crossover interference distance” play a central role?

K Bomblies, G Jones, C Franklin, D Zickler, N Kleckner - Chromosoma, 2016 - Springer
Whole genome duplication is a prominent feature of many highly evolved organisms,
especially plants. When duplications occur within species, they yield genomes comprising …