Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …

Glioblastoma multiforme (GBM) remains the top challenge to radiotherapy with only 25%
one-year survival after diagnosis. Here, we reveal that co-enhancement of mitochondrial …

The identity and unique capacity of cancer stem cells (CSC) to drive tumor growth and
resistance have been challenged in brain tumors. Here we report that cells expressing CSC …

Abstract N6-methyladenosine (m6A) is the most prevalent internal RNA modification in
mammals that regulates homeostasis and function of modified RNA transcripts. Here, we …

The acquisition of genetic alterations, clonal evolution, and the tumor microenvironment
promote cancer progression, metastasis and therapy resistance. These events correspond …

The current preclinical and clinical findings demonstrate that, in addition to the conventional
clinical and pathological indicators that have a prognostic value in radiation oncology, the …

Cancer stem cells (CSCs), known also as tumor-initiating cells, are quiescent, pluripotent,
self-renewing neoplastic cells that were first identified in hematologic tumors and soon after …

Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …