Advances in 3D culture systems for therapeutic discovery and development in brain cancer

J Wanigasekara, PJ Cullen, P Bourke, B Tiwari… - Drug Discovery …, 2023 - Elsevier
Highlights•Existing models for drug discovery and development against glioblastoma
multiforme (GBM) have limitations.•We review advances in 3D systems that promise more …

Bottom‐up versus top‐down strategies for morphology control in polymer‐based biomedical materials

AB Cook, TD Clemons - Advanced NanoBiomed Research, 2022 - Wiley Online Library
The size and shape of polymer materials is becoming an increasingly important property in
accessing new functions and applications of nano‐/microparticles in many scientific fields …

[HTML][HTML] Supramolecular organic nanotubes for drug delivery

VS Saji - Materials Today Advances, 2022 - Elsevier
Organic nanotubes (ONTs) have entranced considerable research attention for their
potential applications in drug delivery, sensors, catalysts, optical devices …

A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models

N Sadeghipour, SU Kumar, TF Massoud… - Scientific Reports, 2022 - nature.com
Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have
limited success because most patients develop chemoresistance. Alternative strategies are …

Organic nanotubes for smart anticorrosion and antibiofouling coatings

VS Saji - npj Materials Degradation, 2022 - nature.com
The easy and scalable synthesis, biocompatibility, one-dimensionality, high aspect ratio,
viability for surface modifications, and the ability for cargo-loading and release make organic …

Chitosan-based DDSs for pH/hypoxia dual-triggered DOX delivery: Facile morphology modulation for higher in vitro cytotoxicity

P Xie, P Liu - Carbohydrate Polymers, 2022 - Elsevier
The morphology of the drug delivery systems (DDSs) has been recognized to play an
important role in their phagocytosis, cellular interaction and distribution. However, it is a …

Photocurable Acrylic-Resin-Based Tubular Micromotors with Smart External Surfaces

M Hashimoto, Y Akashi, Y Sakai… - ACS Applied Polymer …, 2024 - ACS Publications
We present a distinctive synthesis method for photocurable acrylic-resin-based tubular
micromotors characterized by smart external surfaces and augmented functionalities …

Well-defined polyethylene glycol microscale hydrogel blocks containing gold nanorods for dual photothermal and chemotherapeutic therapy

B Newland, J Starke, C Bastiancich, DPN Gonçalves… - Pharmaceutics, 2022 - mdpi.com
Local drug delivery offers a means of achieving a high concentration of therapeutic agents
directly at the tumor site, whilst minimizing systemic toxicity. For heterogenous cancers such …

Novel Therapeutic Approaches to Treat Brain Cancer Combining 3D Cell Culture Models, Cold Atmospheric Plasma and Airborne Acoustic

J Wanigasekara - 2023 - arrow.tudublin.ie
Abstract Glioblastoma (GBM), an adult-type diffuse grade 4 glioma (IDH wild type), is the
most prevalent, aggressive, fatal, highly vascularized, malignant primary brain tumour in …