Early Alzheimer's disease pathology in human cortex involves transient cell states
Cellular perturbations underlying Alzheimer's disease (AD) are primarily studied in human
postmortem samples and model organisms. Here, we generated a single-nucleus atlas from …
postmortem samples and model organisms. Here, we generated a single-nucleus atlas from …
The effectiveness of various CSF diversion surgeries in idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis
A Salih, A Arif, M Varadpande, RT Fernandes… - …, 2024 - thelancet.com
Background Idiopathic normal pressure hydrocephalus (iNPH) is commonly treated using
cerebrospinal fluid (CSF) diversion procedures, most commonly ventriculoperitoneal (VP) …
cerebrospinal fluid (CSF) diversion procedures, most commonly ventriculoperitoneal (VP) …
Utility of cortical tissue analysis in normal pressure hydrocephalus
ABW Greenberg, KY Mekbib, NH Mehta… - Cerebral …, 2024 - academic.oup.com
Clinical improvement following neurosurgical cerebrospinal fluid shunting for presumed
idiopathic normal pressure hydrocephalus is variable. Idiopathic normal pressure …
idiopathic normal pressure hydrocephalus is variable. Idiopathic normal pressure …
Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients
H Lukkarinen, A Jeppsson, C Wikkelsö… - Fluids and Barriers of …, 2022 - Springer
Background The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical
features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive. We …
features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive. We …
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques
T Natunen, H Martiskainen, M Marttinen… - Molecular …, 2020 - Springer
Background Alzheimer's disease (AD) is the most common neurodegenerative disease and
type 2 diabetes (T2D) plays an important role in conferring the risk for AD. Although AD and …
type 2 diabetes (T2D) plays an important role in conferring the risk for AD. Although AD and …
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus
S Weiner, A Junkkari, M Sauer, A Luikku… - Fluids and Barriers of …, 2023 - Springer
Abstract Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult
hydrocephalus that is clinically characterized by progressive gait impairment, cognitive …
hydrocephalus that is clinically characterized by progressive gait impairment, cognitive …
Safety and effectiveness of the assessment and treatment of idiopathic normal pressure hydrocephalus in the Adult Hydrocephalus Clinical Research Network
MA Williams, SJ Nagel, J Golomb, H Jensen… - Journal of …, 2022 - thejns.org
OBJECTIVE The aim of this study was to describe the processes and outcomes associated
with patients at five sites in the Adult Hydrocephalus Clinical Research Network (AHCRN) …
with patients at five sites in the Adult Hydrocephalus Clinical Research Network (AHCRN) …
[HTML][HTML] Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states
Cellular perturbations underlying Alzheimer's disease are primarily studied in human
postmortem samples and model organisms. Here we generated a single-nucleus atlas from …
postmortem samples and model organisms. Here we generated a single-nucleus atlas from …
Motor skills, cognitive impairment, and quality of life in normal pressure hydrocephalus: early effects of shunt placement
M Hülser, H Spielmann, J Oertel, C Sippl - Acta Neurochirurgica, 2022 - Springer
Background Traditionally, clinical findings of normal pressure hydrocephalus are mainly
characterized by the Hakim triad. The aim of this study is to evaluate the performance of …
characterized by the Hakim triad. The aim of this study is to evaluate the performance of …
The CERAD neuropsychological battery in patients with idiopathic normal pressure hydrocephalus compared with normal population and patients with mild …
O Nerg, A Junkkari, I Hallikainen… - Journal of …, 2021 - content.iospress.com
Background: The usefulness of CERAD Neuropsychological Battery for describing the
cognitive impairment in idiopathic normal pressure hydrocephalus (iNPH) is unknown …
cognitive impairment in idiopathic normal pressure hydrocephalus (iNPH) is unknown …