Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the
precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as …

The reissner lamprey Lethenteron reissneri, belonging to the class Cyclostomata, serves as
a bridge between invertebrates and jawed vertebrates, and is considered the sister group of …

The placenta is a vital fetal exchange organ connecting mother and baby. Specialised
placental epithelial cells, called trophoblasts, are essential for adequate placental function …

Background: To study whether there is genetic overlap underlying the risk for schizophrenia
spectrum disorders (SSDs) and low intelligence quotient (IQ), we reviewed and summarized …

Simple Summary In the present study, we aimed to construct a methylation diagnostic tool
using urine sediment for the detection of urothelial bladder carcinoma (UBC), and improved …

Protein-coding differences between species often fail to explain phenotypic diversity,
suggesting the involvement of genomic elements that regulate gene expression such as …

Epigenetic mechanisms are important modulators of neurodevelopmental outcomes in the
offspring of animals challenged during pregnancy. Pregnant sows living in a confined …

Purpose: Glaucoma is a leading cause of irreversible blindness. Glaucomatous intraocular
pressure (IOP) triggers deleterious effects, including gliosis, optic nerve (ON) axonal …

Glioblastoma multiforme (GBM) is the most common and deadliest primary brain tumor,
driving patients to death within 15 months after diagnosis (short term survivors, ST), with the …

Background Ovarian cancer (OC) is the most lethal gynecological cancer, worldwide, largely
due to its vague and nonspecific early stage symptoms, resulting in most tumors being found …