In this work, 26 proteins of different structure, function and properties are investigated by
Raman spectroscopy with 488, 532 and 1064 nm laser lines. The excitation lines were …

Diverse mechanisms for pH sensing and cytoplasmic pH homeostasis enable most bacteria
to tolerate or grow at external pH values that are outside the cytoplasmic pH range they must …

Of all the molecular determinants for growth, the hydronium and hydroxide ions are found
naturally in the widest concentration range, from acid mine drainage below pH 0 to soda …

The intestinal microbiome is a critical determinant of human health. Alterations in its
composition have been correlated with chronic disorders, such as obesity and inflammatory …

The development of antibacterial drugs with new mechanisms of action is crucial in
combating the rise of antibiotic-resistant infections. Bacterial carbonic anhydrases (CAs, EC …

Both symbiotic and pathogenic bacteria in the family Coxiellaceae cause morbidity and
mortality in humans and animals. For instance, Coxiella-like endosymbionts (CLEs) improve …

Leptospirillum ferriphilum plays a major role in acidic, metal-rich environments, where it
represents one of the most prevalent iron oxidizers. These milieus include acid rock and …

Among protein families, carbonic anhydrases (CAs, EC 4.2. 1.1) are metalloenzymes
characterized by a common reaction mechanism in all life domains: the carbon dioxide …

Bioleaching microorganisms inhabit extremely acidic environments (pH< 3.0) and can be
used in the biohydrometallurgical industry. They employ several strategies, such as biofilms …

Introduction This review offers an updated perspective on the biomedical applications of
prokaryotic carbonic anhydrases (CAs), emphasizing their potential as targets for drug …