Short telomeres confer risk of degenerative diseases. Chronic psychological stress can lead
to disease through many pathways, and research from in vitro studies to human longitudinal …

With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

Telomeres are nucleoprotein structures that cap the end of each chromosome arm and
function to maintain genome stability. The length of telomeres is known to shorten with each …

Many psychiatric illnesses are associated with early mortality and with an increased risk of
developing physical diseases that are more typically seen in the elderly. Moreover, certain …

Telomere attrition is a proposed hallmark of aging. To evaluate the association of telomere
length (TL) with chronological age across the human lifespan, we conducted a systematic …

Background The exciting discovery that telomere shortening is associated with many health
conditions and that telomere lengths can be altered in response to social and environmental …

Telomere length (TL) predicts the onset of cellular senescence in vitro but the diagnostic
utility of TL measurement in clinical settings is not fully known. We tested the value of TL …

Research in the last decade has explored the length of telomeres, the protective ends of
eukaryotic chromosomes, as a biomarker for the cumulative effects of environmental …

This manuscript reviews recent evidence supporting the utility of telomeres and
mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse …

Background: Telomere length is a putative biomarker of ageing, morbidity and mortality. Its
application is hampered by lack of widely applicable reference ranges and uncertainty …