Malaria chemoprevention and drug resistance: a review of the literature and policy implications
CV Plowe - Malaria Journal, 2022 - Springer
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …
Prevalence of potential mediators of artemisinin resistance in African isolates of Plasmodium falciparum
Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …
effective interventions. Malaria control gained traction after the introduction of artemisinin …
Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes
AGB Tuedom, EM Sarah-Matio, CEE Moukoko… - PLoS …, 2021 - journals.plos.org
The spread of Plasmodium falciparum resistant parasites remains one of the major
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …
Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular …
VS Koko, M Warsame, B Vonhm, MK Jeuronlon… - Malaria Journal, 2022 - Springer
Background Artesunate–amodiaquine (ASAQ) and Artemether–lumefantrine (AL) are the
recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia …
recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia …
Effect of three years' seasonal malaria chemoprevention on molecular markers of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine and …
Background In 2012, seasonal malaria chemoprevention (SMC) was recommended as
policy for malaria control by the World Health Organization (WHO) in areas of highly …
policy for malaria control by the World Health Organization (WHO) in areas of highly …
A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates …
Background Malaria is a major public health issue with substantial risks among vulnerable
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …
Molecular surveillance of Kelch 13 polymorphisms in Plasmodium falciparum isolates from Kenya and Ethiopia
Background Timely molecular surveillance of Plasmodium falciparum kelch 13 (k13) gene
mutations is essential for monitoring the emergence and stemming the spread of artemisinin …
mutations is essential for monitoring the emergence and stemming the spread of artemisinin …
Assessment of genetic polymorphisms associated with malaria antifolate resistance among the population of Libreville, Gabon
SD Dinzouna-Boutamba, BA Iroungou, FL Akombi… - Malaria Journal, 2023 - Springer
Background Gabon is a malaria-threatened country with a stable and hyperendemic
transmission of Plasmodium falciparum monoinfection. Malaria drug resistance is widely …
transmission of Plasmodium falciparum monoinfection. Malaria drug resistance is widely …
Bias-corrected maximum-likelihood estimation of multiplicity of infection and lineage frequencies
M Hashemi, KA Schneider - PloS one, 2021 - journals.plos.org
Background The UN's Sustainable Development Goals are devoted to eradicate a range of
infectious diseases to achieve global well-being. These efforts require monitoring disease …
infectious diseases to achieve global well-being. These efforts require monitoring disease …
Temporal trends in molecular markers of drug resistance in Plasmodium falciparum in human blood and profiles of corresponding resistant markers in mosquito …
Background Over the last two decades, the scale-up of vector control and changes in the first-
line anti-malarial, from chloroquine (CQ) to sulfadoxine-pyrimethamine (SP) and then to …
line anti-malarial, from chloroquine (CQ) to sulfadoxine-pyrimethamine (SP) and then to …