Mitochondrial dysfunction is one of the hallmarks of aging. Consistently mitochondrial DNA
(mtDNA) copy number and function decline with age in various tissues. There is increasing …

Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event leading
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD) …

Quercetin, a member of the flavonoids family, is one of the most prominent dietary
antioxidants. It is ubiquitously present in foods including vegetables, fruit, tea and wine as …

ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …

Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

Vitamin E (alpha-tocopherol) is an essential micronutrient and fat-soluble antioxidant with
proposed role in protecting tissues from uncontrolled lipid peroxidation. This vitamin has …

Genome stability is essential for maintaining cellular and organismal homeostasis, but it is
subject to many threats. One ubiquitous threat is from a class of compounds known as …

Rhabdomyolysis is defined as a pathological condition of skeletal muscle cell damage
leading to the release of toxic intracellular material into the blood circulation. Its major …

The derivatives of reactive oxygen metabolites (D-ROM) test has been developed to
determine the amount of oxygen-centered free radicals in a blood sample as a marker of …

Cystic fibrosis is a lethal autosomal recessive condition caused by a defect of the
transmembrane conductance regulator gene that has a key role in cell homeostasis. A …