The complement system was discovered at the end of the 19th century as a heat-labile
plasma component that “complemented” the antibodies in killing microbes, hence the name …

The complement system is a set of immune proteins involved in first-line defense against
pathogens and removal of waste materials. Recent evidence has implicated the complement …

Cumulative Series Index for CRC Handbook of Biochemistry and Molecular Biology; Edition 3
Page 1 ERRATA AND ADDENDA CRC HANDBOOK OF BIOCHEMISTRY AND MOLECULAR …

The complement regulatory enzyme, C3b inactivator (C3bINA), has been purified from
human serum by affinity chromatography on an anti-C3bINA Sepharose column …

These experiments were designed to evaluate the role of macrophage plasma membrane
receptors for the third component of complement (C) and for the Fc portion of IgG in the …

The C3 amplification loop lies at the core of all the complement pathways, rather than the
alternative pathway alone. It is, in evolutionary terms, the oldest part of the complement …

In this paper we re-examine the roles of particle-bound IgG and C3 in phagocytosis of sheep
erythrocytes (E) by monolayers of purified human monocytes and polymorphonuclear …

Short-term cultures of human peripheral blood monocytes were shown to synthesize the
alternative pathway complement components C3, factors B (B) and D (D), and properdin, the …

Conclusions The molecular mechanisms of the alternative pathway are now reasonably well
understood. Intramolecular functional sites are currently being delineated that govern the …

Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to
degrade activated complement proteins C3b and C4b in the presence of cofactors such as …