Enzymatic processing of lignocellulosic biomass: principles, recent advances and perspectives

H Østby, LD Hansen, SJ Horn… - Journal of Industrial …, 2020 - academic.oup.com
Efficient saccharification of lignocellulosic biomass requires concerted development of a
pretreatment method, an enzyme cocktail and an enzymatic process, all of which are …

Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry

B Bissaro, VGH Eijsink - Essays in biochemistry, 2023 - portlandpress.com
The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic
polysaccharide monooxygenases (LPMOs) has profoundly changed our current …

The “life-span” of lytic polysaccharide monooxygenases (LPMOs) correlates to the number of turnovers in the reductant peroxidase reaction

S Kuusk, VGH Eijsink, P Väljamäe - Journal of Biological Chemistry, 2023 - ASBMB
Lytic polysaccharide monooxygenases (LPMOs) are monocopper enzymes that degrade the
insoluble crystalline polysaccharides cellulose and chitin. Besides the H 2 O 2 cosubstrate …

Enhanced in situ H2O2 production explains synergy between an LPMO with a cellulose-binding domain and a single-domain LPMO

AA Stepnov, VGH Eijsink, Z Forsberg - Scientific Reports, 2022 - nature.com
Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that catalyze
oxidative depolymerization of recalcitrant substrates such as chitin or cellulose. Recent work …

On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs)

Z Forsberg, G Courtade - Essays in Biochemistry, 2023 - portlandpress.com
Lytic polysaccharide monooxygenases (LPMOs) have revolutionized our understanding of
how enzymes degrade insoluble polysaccharides. Compared with the substantial …

AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila

P Sun, Z Huang, S Banerjee, MAS Kadowaki… - ACS …, 2023 - ACS Publications
Copper-dependent lytic polysaccharide monooxygenases (LPMOs) classified in Auxiliary
Activity (AA) families are considered indispensable as synergistic partners for cellulolytic …

Controlled depolymerization of cellulose by light-driven lytic polysaccharide oxygenases

B Bissaro, E Kommedal, ÅK Røhr… - Nature …, 2020 - nature.com
Lytic polysaccharide (mono) oxygenases (LPMOs) perform oxidative cleavage of
polysaccharides, and are key enzymes in biomass processing and the global carbon cycle …

Fast and specific peroxygenase reactions catalyzed by fungal mono-copper enzymes

L Rieder, AA Stepnov, M Sørlie, VGH Eijsink - Biochemistry, 2021 - ACS Publications
The copper-dependent lytic polysaccharide monooxygenases (LPMOs) are receiving
attention because of their role in the degradation of recalcitrant biomass and their intriguing …

The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid

AA Stepnov, IA Christensen, Z Forsberg… - FEBS …, 2022 - Wiley Online Library
Monocopper lytic polysaccharide monooxygenases (LPMOs) catalyse oxidative cleavage of
glycosidic bonds in a reductant‐dependent reaction. Recent studies indicate that LPMOs …

Comparison of Six Lytic Polysaccharide Monooxygenases from Thermothielavioides terrestris Shows That Functional Variation Underlies the Multiplicity of LPMO …

M Tõlgo, OA Hegnar, H Østby, A Várnai… - Applied and …, 2022 - Am Soc Microbiol
Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that oxidatively
degrade various polysaccharides. Genes encoding LPMOs in the AA9 family are abundant …