Big data management challenges in health research—a literature review

X Wang, C Williams, ZH Liu… - Briefings in …, 2019 - academic.oup.com
Big data management for information centralization (ie making data of interest findable) and
integration (ie making related data connectable) in health research is a defining challenge in …

Big Data in Laboratory Medicine—FAIR Quality for AI?

TU Blatter, H Witte, CT Nakas, AB Leichtle - Diagnostics, 2022 - mdpi.com
Laboratory medicine is a digital science. Every large hospital produces a wealth of data
each day—from simple numerical results from, eg, sodium measurements to highly complex …

Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database

A Bissett, A Fitzgerald, T Meintjes, PM Mele, F Reith… - GigaScience, 2016 - Springer
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

[HTML][HTML] Challenges in the setup of large-scale next-generation sequencing analysis workflows

P Kulkarni, P Frommolt - Computational and structural biotechnology …, 2017 - Elsevier
Abstract While Next-Generation Sequencing (NGS) can now be considered an established
analysis technology for research applications across the life sciences, the analysis …

Big data in biology: the hope and present-day challenges in it

S Pal, S Mondal, G Das, S Khatua, Z Ghosh - Gene Reports, 2020 - Elsevier
The wave of new technologies has opened up the opportunity for cost-effective generation of
high-throughput profiles of biological systems. This is generating tons of biological data. It is …

[HTML][HTML] Evaluation of relational and NoSQL database architectures to manage genomic annotations

WL Schulz, BG Nelson, DK Felker, TJS Durant… - Journal of biomedical …, 2016 - Elsevier
While the adoption of next generation sequencing has rapidly expanded, the informatics
infrastructure used to manage the data generated by this technology has not kept pace …

Big Data: the challenge for small research groups in the era of cancer genomics

AM Noor, L Holmberg, C Gillett, A Grigoriadis - British journal of cancer, 2015 - nature.com
In the past decade, cancer research has seen an increasing trend towards high-throughput
techniques and translational approaches. The increasing availability of assays that utilise …

Integration and visualization of translational medicine data for better understanding of human diseases

V Satagopam, W Gu, S Eifes, P Gawron… - Big data, 2016 - liebertpub.com
Translational medicine is a domain turning results of basic life science research into new
tools and methods in a clinical environment, for example, as new diagnostics or therapies …

Evaluating several design patterns and trends in big data warehousing systems

C Costa, MY Santos - … : 30th International Conference, CAiSE 2018, Tallinn …, 2018 - Springer
Abstract The Big Data characteristics, namely volume, variety and velocity, currently
highlight the severe limitations of traditional Data Warehouses (DWs). Their strict relational …

The SusCity big data warehousing approach for smart cities

C Costa, MY Santos - Proceedings of the 21st international database …, 2017 - dl.acm.org
Nowadays, the concept of Smart City provides a rich analytical context, highlighting the need
to store and process vast amounts of heterogeneous data flowing at different velocities. This …