Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …

Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

Myeloid-derived suppressor cells (MDSCs) expand during pathological conditions in both
humans and mice and their presence is linked to poor clinical outcomes for cancer patients …

Although radiotherapy (RT) has achieved great success in the treatment of non-small cell
lung cancer (NSCLC), local relapses still occur and abscopal effects are rarely seen even …

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature
myeloid cells with immunosuppressive properties. In cancer patients, the expression of lectin …

Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes that negatively regulate the immune response to cancer and chronic infections …

Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population
comprised of immature myeloid cells and myeloid progenitors with very potent …

Low-density granulocytes (LDGs) have been characterized as important immune cells
during healthy and disease states in humans, including microbial infections, cancer, and …

Background Recent studies have demonstrated that blocking the PI3Kδ signalling enzyme
(by administering a small molecule inhibitor, PI-3065) can potently improve the anti-tumour T …

The maternal immune system is vital in maintaining immunotolerance to the semiallogeneic
fetus for a successful pregnancy. Although studies have shown that myeloid-derived …