Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …

Sirtuins are a class of enzymes with nicotinamide adenine dinucleotide (NAD)-dependent
protein lysine deacylase function. By deacylating various substrate proteins, including …

Aurones are very simple, promising anticancer lead molecules containing three rings (A, B
and C). A very slight structural variation in the aurones elicits diverse affinity and specificity …

The ultrasonic energy has been revisited and applied for the synthesis of bioactive
molecules in a short time and green method. These compounds can exhibit anticancer …

A library comprising 44 diversely substituted aurones derivatives was synthesized by
straightforward aldol condensation reactions of benzofuranones and the appropriately …

Sirtuins are NAD+-dependent deac (et) ylases with different subcellular localization. The
sirtuins' family is composed of seven members, named SIRT-1 to SIRT-7. Their substrates …

Aurones are an interesting, but little studied member of the flavanoid family of natural
products. Of the various methods available for their synthesis, the simplest involves the …

A series of aurone Mannich base derivatives were designed, synthesized and evaluated as
multifunctional agents for the treatment of Alzheimer's disease. In vitro assays demonstrated …

A series of 4-hydroxyl aurone derivatives were designed synthesized and evaluated as
potential multifunctional agents for the treatment of Alzheimer's disease. The results …

This article provides generalized and systematic overview of data on the synthesis,
stereoisomerism, and reactivity of aurones (2-benzylidenebenzofuran-3 (2 Н)-ones) …