[HTML][HTML] Phage therapy: From biological mechanisms to future directions
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Considerations for the use of phage therapy in clinical practice
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …
renewed interest in phage therapy as an alternative or adjunct to conventional …
The human virome: assembly, composition and host interactions
G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Bacteriophages are the most abundant members of the microbiota and have the potential to
shape gut bacterial communities. Changes to bacteriophage composition are associated …
shape gut bacterial communities. Changes to bacteriophage composition are associated …
Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double …
Background Wound infections are the main cause of sepsis in patients with burns and
increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are …
increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are …
[HTML][HTML] Phage therapy in the resistance era: where do we stand and where are we going?
Purpose Widespread antibiotic-resistant bacteria are threatening the arsenal of existing
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …
Interactions between bacteriophage, bacteria, and the mammalian immune system
JD Van Belleghem, K Dąbrowska, M Vaneechoutte… - Viruses, 2018 - mdpi.com
The human body is host to large numbers of bacteriophages (phages)–a diverse group of
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …
Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection
JM Sweere, JD Van Belleghem, H Ishak, MS Bach… - Science, 2019 - science.org
INTRODUCTION We have identified previously unsuspected, directly pathogenic roles for
bacteriophage (phage) virions in bacterial infections. In particular, we report that …
bacteriophage (phage) virions in bacterial infections. In particular, we report that …