[HTML][HTML] Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response
DR Wang, XL Wu, YL Sun - Signal transduction and targeted therapy, 2022 - nature.com
Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …
malignant cells but also an altered immune response. The inhibition and reprogramming of …
[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
[HTML][HTML] CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope
V Karn, S Sandhya, W Hsu, D Parashar… - Cancer Cell …, 2022 - Springer
Cancer is one of the major causes of mortality worldwide, therefore it is considered a major
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
[HTML][HTML] CRISPR-Cas assisted diagnostics: A broad application biosensing approach
In addition to its remarkable genome editing capability, the CRISPR-Cas system has proven
to be very effective in many fields of application, including the biosensing of pathogenic …
to be very effective in many fields of application, including the biosensing of pathogenic …
Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies
The clinical management of bladder cancer (BC) has become an increasing challenge due
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …
[HTML][HTML] Nanomedicine in hepatocellular carcinoma: a new frontier in targeted cancer treatment
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death and is
associated with a dismal median survival of 2–9 months. The fundamental limitations and …
associated with a dismal median survival of 2–9 months. The fundamental limitations and …
[HTML][HTML] Current strategies employed in the manipulation of gene expression for clinical purposes
HC Tsai, V Pietrobon, M Peng, S Wang, L Zhao… - Journal of Translational …, 2022 - Springer
Abnormal gene expression level or expression of genes containing deleterious mutations
are two of the main determinants which lead to genetic disease. To obtain a therapeutic …
are two of the main determinants which lead to genetic disease. To obtain a therapeutic …
[HTML][HTML] Targeting cancer with CRISPR/Cas9-based therapy
K Balon, A Sheriff, J Jacków, Ł Łaczmański - International journal of …, 2022 - mdpi.com
Cancer is a devastating condition characterised by the uncontrolled division of cells with
many forms remaining resistant to current treatment. A hallmark of cancer is the gradual …
many forms remaining resistant to current treatment. A hallmark of cancer is the gradual …
[HTML][HTML] The interplay between T cells and cancer: The basis of immunotherapy
C Chen, X Liu, CY Chang, HY Wang, RF Wang - Genes, 2023 - mdpi.com
Over the past decade, immunotherapy has emerged as one of the most promising
approaches to cancer treatment. The use of immune checkpoint inhibitors has resulted in …
approaches to cancer treatment. The use of immune checkpoint inhibitors has resulted in …
[HTML][HTML] CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer
Breast cancer (BC) is the most common type of cancer in women at the global level and the
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …