Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

Trillions of microbes reside in the human body and participate in multiple physiological and
pathophysiological processes that affect host health throughout the life cycle. The …

Objective Necrotising enterocolitis (NEC) is a devastating intestinal disease primarily
affecting preterm infants. The underlying mechanisms are poorly understood: mother's own …

Metabolomic analysis of human biospecimens had progressed quickly over the past
decade. Technological and methodological advances have led to the comprehensive …

Highlights•In utero microbial stimulation modulates both prenatal and postnatal immune cell
development.•Unique neonatal gut microenvironment allows for progressive colonization of …

Background Intestinal dysbiosis may contribute to the pathogenesis of necrotising
enterocolitis (NEC) in very preterm or very low birth weight infants. Dietary supplementation …

Bifidobacteria are among the predominant microorganisms during infancy, being a dominant
microbial group in the healthy breastfed infant and playing a crucial role in newborns and …

Aim This narrative review summarises the benefits of maternal breastmilk to both the infant
and the mother, specifically the benefits that relate to modification of the infant microbiome …

Sepsis is a complex of life-threating organ dysfunction in critically ill patients, with a primary
infectious cause or through secondary infection of damaged tissues. The systemic …

Chronic hepatitis B infection is one of the major etiological causes of liver failure, cirrhosis,
and hepatocellular carcinoma (HCC) worldwide. This condition cannot be completely cured …