[HTML][HTML] Sources and clinical applications of mesenchymal stem cells: state-of-the-art review

R Berebichez-Fridman… - Sultan Qaboos University …, 2018 - ncbi.nlm.nih.gov
First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem
cells found throughout the body that share a fixed set of characteristics. Discovered initially …

Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use

GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …

Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure …

EC Perin, JT Willerson, CJ Pepine, TD Henry, SG Ellis… - Jama, 2012 - jamanetwork.com
Context Previous studies using autologous bone marrow mononuclear cells (BMCs) in
patients with ischemic cardiomyopathy have demonstrated safety and suggested efficacy …

Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis

V Jeevanantham, M Butler, A Saad, A Abdel-Latif… - Circulation, 2012 - Am Heart Assoc
Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the …

JH Traverse, TD Henry, SG Ellis, CJ Pepine… - Jama, 2011 - jamanetwork.com
Context Clinical trial results suggest that intracoronary delivery of autologous bone marrow
mononuclear cells (BMCs) may improve left ventricular (LV) function when administered …

Mesenchymal stem cell therapy: A promising cell‐based therapy for treatment of myocardial infarction

AES Shafei, MA Ali, HG Ghanem… - The journal of gene …, 2017 - Wiley Online Library
For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …

Immunogenicity of allogeneic mesenchymal stem cells

S Schu, M Nosov, L O'Flynn, G Shaw… - Journal of cellular …, 2012 - Wiley Online Library
Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low
levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion …

Assessment and optimization of cell engraftment after transplantation into the heart

JV Terrovitis, RR Smith, E Marbán - Circulation research, 2010 - Am Heart Assoc
Myocardial regeneration using stem and progenitor cell transplantation in the injured heart
has recently become a major goal in the treatment of cardiac disease. Experimental studies …

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left …

M Tendera, W Wojakowski, W Rużyłło… - European heart …, 2009 - academic.oup.com
Aims Comparison of intracoronary infusion of bone marrow (BM)-derived unselected
mononuclear cells (UNSEL) and selected CD34+ CXCR4+ cells (SEL) in patients with acute …

Hypoxic culture conditions as a solution for mesenchymal stem cell based regenerative therapy

N Haque, MT Rahman, NH Abu Kasim… - The Scientific World …, 2013 - Wiley Online Library
Cell‐based regenerative therapies, based on in vitro propagation of stem cells, offer
tremendous hope to many individuals suffering from degenerative diseases that were …