A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Cyclic peptide drugs approved in the last two decades (2001–2021)

H Zhang, S Chen - RSC Chemical Biology, 2022 - pubs.rsc.org
In contrast to the major families of small molecules and antibodies, cyclic peptides, as a
family of synthesizable macromolecules, have distinct biochemical and therapeutic …

Developments in glycopeptide antibiotics

MAT Blaskovich, KA Hansford, MS Butler… - ACS Infectious …, 2018 - ACS Publications
Glycopeptide antibiotics (GPAs) are a key weapon in the fight against drug resistant
bacteria, with vancomycin still a mainstream therapy against serious Gram-positive …

Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials

KMG O'Connell, JT Hodgkinson… - Angewandte Chemie …, 2013 - Wiley Online Library
The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th
century completely revolutionized clinical practices and helped to facilitate the development …

Glycopeptide antibiotics: back to the future

MS Butler, KA Hansford, MAT Blaskovich… - The Journal of …, 2014 - nature.com
Glycopeptide antibiotics have been a key weapon in the fight against bacterial infections for
over half a century, with the progenitors, vancomycin (1) and teicoplanin (2), still used …

Mechanisms of daptomycin resistance in Staphylococcus aureus: role of the cell membrane and cell wall

AS Bayer, T Schneider, HG Sahl - … of the New York Academy of …, 2013 - Wiley Online Library
The bactericidal, cell membrane–targeting lipopeptide antibiotic daptomycin (DAP) is an
important agent in treating invasive Staphylococcus aureus infections. However, there have …

Approved glycopeptide antibacterial drugs: mechanism of action and resistance

D Zeng, D Debabov, TL Hartsell… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
The glycopeptide antimicrobials are a group of natural product and semisynthetic
glycosylated peptides that show antibacterial activity against Gram-positive organisms …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Macrocyclic drugs and synthetic methodologies toward macrocycles

X Yu, D Sun - Molecules, 2013 - mdpi.com
Macrocyclic scaffolds are commonly found in bioactive natural products and pharmaceutical
molecules. So far, a large number of macrocyclic natural products have been isolated and …