One of the simplest organic functional groups, the alkyne, offers a broad canvas for the
design of cascade transformations in which up to three new bonds can be added to each of …

The classical repertoire of synthetic organic chemistry is short of methods that allow triple
bonds to be transformed into (E)-alkenes with high selectivity in the presence of other …

The chemistry of acetylenes has been extensively used in organic synthesis.[1] In recent
decades, the functionalization of the triple bond by using metal catalysis has complemented …

We report the first example of a traceless directing group in a radical cascade. The chemo-
and regioselectivity of the initial attack in skipped oligoalkynes is controlled by propargyl OR …

In this Review, we present an overview of hydrostannation of alkynes until the end of 2018.
The mechanism of the tin hydride addition on a triple bond in the presence of metal catalysts …

A significant number of antiviral agents used in clinical practice are amino acids, short
peptides, or peptidomimetics. Among them, several HIV protease inhibitors (eg lopinavir …

A unified kinetic theory for both initiation and autoxidation reactions of Et3B and O2 is put
forth, and then divided into low-oxygen and high-oxygen experimental regimes for …

Lactimidomycin (1) was described in the literature as an exquisitely potent cell migration
inhibitor. Encouraged by this claim, we developed a concise and scalable synthesis of this …

A versatile synthetic route to distannyl-substituted polyarenes was developed via double
radical peri-annulations. The cyclization precursors were equipped with propargylic OMe …

The first total synthesis of the potent antibiotic disciformycin B (2) is described, which is
exceptionally isomerization‐prone and transforms into disciformycin A (1) even under …